Peanut allergy has a genetic link: Study

April 09, 2016

For the study they involved 71 English, Dutch, and Irish patients with positive peanut results in an oral food test, where the patient eats the food while a physician watches carefully for symptoms. Their genetic findings were compared with 1,000 controls from the English population. The investigation was then repeated in 309 Canadians with peanut allergies and another 891 controls from the general Canadian population. Authors concluded, ???Taken together, our experimental data from four populations of European origin demonstrate a strong and significant association of loss-of-function mutations within the filaggrin gene with clinically significant peanut allergy.??? It is estimated about one in 50 Canadian children has a peanut allergy, and about one to two per cent of these can have severe or life-threatening reactions, according to Anaphylaxis Canada.

The Canadian peanut allergy study was supported by grants from the Canadian Dermatology Foundation, the University of Saskatchewan, Department of Medicine Research Fund, the Foundations of the McGill University Health Centre and the Montreal Children's Hospital as well as grants from the Canadian Allergy, Asthma, and Immunology Foundation and the AllerGen Network of Centres of Excellence.