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AACR to host special conference on colorectal cancer

March 05, 2016

In the fruit fly, Dr Martinho and his collaborators propose to unravel the behaviour of one of these enzymes in order to understand its role in the growth and division of cells.

The modifications carried out by this enzyme affect a wide range of cellular functions during cell division and apoptosis (programmed cell death) essential for the normal balance of the organism, but they may also be involved in the development of cancer.

He explained: "We will focus on the enzyme San, to try to identify what it acts upon in the cell, how it is regulated, the consequences of its actions and, ultimately, its effect on how cells divide.

"Our approach will allow a better understanding of the impact of these modifications in healthy cells and cancer development in a living context closer to our own, rather than in human cells grown in test tubes or in unicellular organisms, such as yeast, as previous studies have done."

Source: Association for International Cancer Research